What is the defining buzzword associated with Henoch-Schonlein purpura?

What is the defining buzzword associated with Henoch-Schonlein purpura?

• A. Palpable purpura
• B. Macrocytic anemia
• C. Hematuria
• D. Skin rash

Answer: (A)

Henoch-Schonlein purpura (HSP), also known as IgA vasculitis, is characterized by a specific type of skin manifestation known as palpable purpura. This purpura typically appears as raised bruises or spots on the skin, most commonly located on the buttocks and legs of affected children. The condition is primarily associated with a systemic vasculitis that involves small blood vessels, leading to the characteristic skin changes. The presence of palpable purpura is crucial for diagnosis and distinguishes HSP from other conditions that may also involve purpura, which could be non-palpable or have different clinical implications. While hematuria can occur in HSP due to renal involvement, and a skin rash is a general term that could apply to various dermatological conditions, it is the specific term "palpable purpura" that accurately encapsulates the hallmark feature of this disease. This term emphasizes both the physical examination findings and the underlying pathophysiological process at play in HSP.

Henoch-Schonlein purpura (HSP), also known as IgA vasculitis, is characterized by a specific type of skin manifestation known as palpable purpura. This purpura typically appears as raised bruises or spots on the skin, most commonly located on the buttocks and legs of affected children. The condition is primarily associated with a systemic vasculitis that involves small blood vessels, leading to the characteristic skin changes.

The presence of palpable purpura is crucial for diagnosis and distinguishes HSP from other conditions that may also involve purpura, which could be non-palpable or have different clinical implications. While hematuria can occur in HSP due to renal involvement, and a skin rash is a general term that could apply to various dermatological conditions, it is the specific term "palpable purpura" that accurately encapsulates the hallmark feature of this disease. This term emphasizes both the physical examination findings and the underlying pathophysiological process at play in HSP.