What type of skin manifestation is observed in Henoch-Schonlein purpura?

What type of skin manifestation is observed in Henoch-Schonlein purpura?

• A. Petechiae
• B. Vesicular lesions
• C. Raised vasculitic rash
• D. Generalized rash

Answer: (C)

In Henoch-Schonlein purpura (HSP), the skin manifestation primarily observed is a raised vasculitic rash, which is often characterized by palpable purpura. This type of rash typically appears as raised, red or purple spots that can be seen on the buttocks, legs, and sometimes the upper body. The elevated nature of the rash is due to inflammation of the small blood vessels in the skin, which leads to extravasation of blood and subsequent development of purpura. HSP is a small-vessel vasculitis that primarily affects children and can result in a classic triad of symptoms: skin rash, abdominal pain, and arthritis or arthralgia. The skin lesions themselves signify systemic involvement and are a key clinical feature used for diagnosis. While petechiae can occur in various conditions involving capillary fragility, the significant feature in HSP is the palpable and raised aspect of the purpuric rash, distinguishing it from other potential skin manifestations. Vesicular lesions would indicate a different pathology, often associated with infections or other dermatological conditions, and a generalized rash lacks the specificity and distinct characteristics of the rash seen in HSP.

In Henoch-Schonlein purpura (HSP), the skin manifestation primarily observed is a raised vasculitic rash, which is often characterized by palpable purpura. This type of rash typically appears as raised, red or purple spots that can be seen on the buttocks, legs, and sometimes the upper body. The elevated nature of the rash is due to inflammation of the small blood vessels in the skin, which leads to extravasation of blood and subsequent development of purpura.

HSP is a small-vessel vasculitis that primarily affects children and can result in a classic triad of symptoms: skin rash, abdominal pain, and arthritis or arthralgia. The skin lesions themselves signify systemic involvement and are a key clinical feature used for diagnosis.

While petechiae can occur in various conditions involving capillary fragility, the significant feature in HSP is the palpable and raised aspect of the purpuric rash, distinguishing it from other potential skin manifestations. Vesicular lesions would indicate a different pathology, often associated with infections or other dermatological conditions, and a generalized rash lacks the specificity and distinct characteristics of the rash seen in HSP.